ACTB-1003

Catalog No.: A14431

FGFR1 inhibitor

ACTB-1003

ACTB-1003 Chemical Structure

CAS NO. 939805-30-8

ACTB-1003 is an oral kinase inhibitor targeting cancer mutations (FGFR inhibition), angiogenesis (inhibition of VEGFR2 and Tie-2) and induces apoptosis (targeting RSK and p70S6K, downstream of PI3 kinase).

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
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Biological Activity

ACTB-1003 is an oral kinase inhibitor targeting cancer mutations (FGFR inhibition), angiogenesis (inhibition of VEGFR2 and Tie-2) and induces apoptosis (targeting RSK and p70S6K, downstream of PI3 kinase).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.91 mL 84.53 mL 169.05 mL
0.5 mM 3.38 mL 16.91 mL 33.81 mL
1 mM 1.69 mL 8.45 mL 16.91 mL
5 mM 0.34 mL 1.69 mL 3.38 mL

*The above data is based on the productmolecular weight 591.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14431
Actions Inhibitor
CAS No. 939805-30-8
Formula C27H26F5N7O3
M. Wt 591.53
Purity >98%
Synonyms ACTB1003, ACTB 1003
SMILES COCC1=C(N2C(=C1C3=CC(=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)F)C(=NC=N2)N)CN5CCOCC5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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