Fig. 1 · Structure
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ACTH (1-17)
Melanocortin Receptor Agonist
ACTH (1-17) is a potent agonist of the human melanocortin 1 (MC1) receptor, exhibiting a Ki of 0.21 nM. This adrenocorticotropin analogue plays a critical role in modulating melanogenesis and has significant implications for research in skin pigmentation and endocrine regulation. Its efficacy makes it a valuable tool for studies focused on melanocortin signaling pathways and related therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 7266-47-9 |
| Applications | Melanocortin Receptor Agonist |
| Formula | C95H145N29O23S |
| Molecular Weight | 2093.41 |
| Synonyms | α1-17-ACTH |
| SMILES | CSCCC(NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CO)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.