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ACTH (11-24)

Catalog No.: A61655
ACTH Receptor Antagonist
ACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist that modulates cortisol release through the inhibition of ACTH receptors. This peptide fragment serves as a valuable tool for investigating endocrine regulation and its effects within the central nervous system. ACTH (11-24) is particularly useful in studies related to stress response, neuroendocrine function, and potential therapeutic applications in disorders linked to ACTH signaling.
ACTH (11-24) 4237-93-8 ACTH Receptor Antagonist
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Size Price Stock Qty
1mg
$45.00
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5mg
$90.00
In stock
10mg
$130.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist that modulates cortisol release through the inhibition of ACTH receptors. This peptide fragment serves as a valuable tool for investigating endocrine regulation and its effects within the central nervous system. ACTH (11-24) is particularly useful in studies related to stress response, neuroendocrine function, and potential therapeutic applications in disorders linked to ACTH signaling.
Product Information
Catalog NumA61655
FormulaC77H134N24O16
Molecular Weight1652.04
CAS Number4237-93-8
SequenceLys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
Sequence shorteningKPVGKKRRPVKVYP
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@H]1N(C([C@H](CCCCN)N)=O)CCC1)[C@H](C)C)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(O)=O)CCC3)CC4=CC=C(O)C=C4)=O)C(C)C)=O)CCCCN)=O)C(C)C)=O)CCC2
SynonymsAdrenocorticotropic Hormone (11-24)
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