Fig. 1 · Structure
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ACTH (11-24)
ACTH Receptor Antagonist
ACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist that modulates cortisol release through the inhibition of ACTH receptors. This peptide fragment serves as a valuable tool for investigating endocrine regulation and its effects within the central nervous system. ACTH (11-24) is particularly useful in studies related to stress response, neuroendocrine function, and potential therapeutic applications in disorders linked to ACTH signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 4237-93-8 |
| Applications | ACTH Receptor Antagonist |
| Formula | C77H134N24O16 |
| Molecular Weight | 1652.04 |
| Synonyms | Adrenocorticotropic Hormone (11-24) |
| SMILES | C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@H]1N(C([C@H](CCCCN)N)=O)CCC1)[C@H](C)C)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(O)=O)CCC3)CC4=CC=C(O)C=C4)=O)C(C)C)=O)CCCCN)=O)C(C)C)=O)CCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.