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ACTH (6-24) (human)

Steroidogenesis Inhibitor

ACTH (6-24) (human) is an ACTH fragment that acts as a competitive inhibitor of steroidogenesis. It effectively inhibits the production of corticosterone and the accumulation of cAMP induced by ACTH (1-39) and ACTH (5-24), demonstrating Kd values of 13.4 nM and 3.4 nM, respectively. This reagent is valuable for research applications exploring the mechanisms of adrenal hormone regulation and the physiological effects of steroidogenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	33512-65-1
Applications	Steroidogenesis Inhibitor
Formula	C₁₁₁H₁₇₅N₃₅O₂₁
Molecular Weight	2335.80
Synonyms	Adrenocorticotropic hormone (6-24)
SMILES	C([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)N)=O)=O)CCCNC(=N)N)=O)C(NCC(N[C@H](C(=O)N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(O)=O)CCC5)CC6=CC=C(O)C=C6)=O)C(C)C)=O)CCCCN)=O)[C@@H](C)C)=O)CCC4)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)CCC3)CCCCN)=O)=O)C=7C=8C(NC7)=CC=CC8

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.