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Ad-JQ1

Target Protein Ligand-Linker Conjugate

Ad-JQ1 is a Target Protein Ligand-Linker Conjugate designed to selectively target BRD4. This compound combines a BRD4 ligand with a PROTAC linker, facilitating the recruitment of E3 ubiquitin ligases to promote targeted protein degradation. Ad-JQ1 is valuable for constructing PROTACs, such as β-NF-JQ1, thus enabling advanced research in cellular signaling and cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2497485-14-8
Applications	Target Protein Ligand-Linker Conjugate
Formula	C₃₇H₄₇ClN₆O₄S
Molecular Weight	707.32
SMILES	O=C(NCCOCCOCCNC(C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1)=O)CC5(C[C@@H](C6)C7)C[C@@H]7C[C@@H]6C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.