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Adamtsostatin 4

Catalog No.: A69305
Anti-angiogenic Peptide
Adamtsostatin 4 is an anti-angiogenic peptide that inhibits angiogenesis by targeting vascular endothelial growth factor (VEGF) signaling pathways. This peptide demonstrates significant biological activity in reducing endothelial cell proliferation and migration, making it a valuable tool in cancer research and therapeutic development aimed at combating tumors. Its application extends to studies focused on angiogenesis-related diseases and the evaluation of anti-angiogenic strategies.
Adamtsostatin 4 929554-73-4 Anti-angiogenic Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAdamtsostatin 4 is an anti-angiogenic peptide that inhibits angiogenesis by targeting vascular endothelial growth factor (VEGF) signaling pathways. This peptide demonstrates significant biological activity in reducing endothelial cell proliferation and migration, making it a valuable tool in cancer research and therapeutic development aimed at combating tumors. Its application extends to studies focused on angiogenesis-related diseases and the evaluation of anti-angiogenic strategies.
Product Information
Catalog NumA69305
FormulaC80H121N27O27S2
Molecular Weight1957.12
CAS Number929554-73-4
Sequence shorteningGPWGDCSRTCGGGVQFSSR
SMILESC([C@H](NC(=O)[C@H]1N(C(CN)=O)CCC1)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CO)=O)CO)=O)=O)CCC(N)=O)=O)[C@@H](C)C)=O)=O)=O)=O)CS)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CO)=O)CS)=O)CC(O)=O)=O)=O)C=3C=4C(NC3)=CC=CC4
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