Fig. 1 · Structure
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ADD-17014
L-Glu Antagonist
ADD-17014 is an L-glutamate (L-Glu) antagonist that inhibits presynaptic excitatory neurotransmission. As a prodrug, it metabolizes to a β-amino alcohol that acts as an NMDA receptor antagonist by binding to the MK-801 site within the receptor channel. This compound exhibits anticonvulsant and anti-ischemic properties, making it a valuable reagent for research on neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and stroke.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 55643-87-3 |
| Applications | L-Glu Antagonist |
| Formula | C13H11ClN4 |
| Molecular Weight | 258.71 |
| SMILES | ClC1=CC=C(N2N=NCC2C3=CC=NC=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.