Fig. 1 · Structure
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Adenosine 3′-monophosphate
Nucleotide
Adenosine 3'-monophosphate (3'-AMP) is a nucleotide that serves as a potent agonist for cyclic AMP production. It enhances cyclic AMP levels in a concentration-dependent manner in NG108-15 cells, making it valuable for studying cellular signaling pathways. Additionally, 3'-AMP is utilized in clinical laboratory settings to assess acid phosphatase activity in human serum, aiding in the diagnosis of conditions such as prostate cancer, metastatic breast cancer, and Gaucher’s disease. Furthermore, it exhibits the ability to inhibit the proliferation of human aortic and coronary vascular smooth muscle cells through the activation of A2B receptors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 84-21-9 |
| Applications | Nucleotide |
| Formula | C10H14N5O7P |
| Molecular Weight | 347.22 |
| Synonyms | 3′-AMP |
| SMILES | NC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]3O)C=N2)=NC=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.