Fig. 1 · Structure
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ADRA1D receptor antagonist 1
Alpha(1D) Adrenoceptor Antagonist
ADRA1D receptor antagonist 1 is a selective and potent antagonist of the alpha-1D adrenoceptor, characterized by a Ki value of 1.6 nM. This compound plays a significant role in modulating adrenergic signaling pathways and is valuable for studies focused on cardiovascular and central nervous system disorders. Its oral bioavailability further enhances its utility in pharmacological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1191908-14-1 |
| Applications | Alpha(1D) Adrenoceptor Antagonist |
| Formula | C15H14Cl2N4O |
| Molecular Weight | 337.20 |
| SMILES | O=C(C1=CC(Cl)=CN([C@@H](C2=CC=CC(C#N)=C2)C)C1=N)N.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.