Fig. 1 · Structure
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Adrenocorticotropic hormone
Tropic Hormone
Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone synthesized in the anterior pituitary gland. It primarily stimulates cortisol secretion from the adrenal cortex through the hypothalamic-pituitary-adrenal (HPA) axis, playing a crucial role in regulating both cortisol and androgen production. Additionally, ACTH influences spermatogenesis and has been shown to mitigate acute inflammation in gout models by inhibiting macrophage polarization to the M1 type, reducing reactive oxygen species (ROS) and proinflammatory factors while preserving mitochondrial function. This hormone is valuable for research in fields such as inflammation, endocrinology, and metabolic diseases including gout and nephrotic syndrome.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9002-60-2 |
| Applications | Tropic Hormone |
| Formula | C207H308N56O58S |
| Molecular Weight | 4541.14 |
| Synonyms | ACTH; Adrenocorticotrophic hormone |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.