Fig. 1 · Structure
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ADX71743
mGlu7 Antagonist
ADX71743 is a highly selective, noncompetitive antagonist of the metabotropic glutamate receptor 7 (mGlu7). This compound demonstrates significant brain penetration, facilitating its efficacy in neurological research. ADX71743 exhibits anxiolytic properties and is utilized in studies exploring treatments for anxiety disorders and related neuropsychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1431641-29-0 |
| Applications | mGlu7 Antagonist |
| Formula | C17H19NO2 |
| Molecular Weight | 269.34 |
| SMILES | O=C1C2=C(OC(CC)=N2)CC(C3=C(C=C(C)C=C3)C)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.