Fig. 1 · Structure
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AF38469
Sortilin Inhibitor
AF38469 is a selective inhibitor of Sortilin, demonstrating an IC50 value of 330 nM. This compound effectively modulates Sortilin-mediated pathways, making it a valuable tool for investigating cellular processes associated with neurodegenerative diseases and metabolic disorders. Its oral bioavailability facilitates in vivo studies, allowing researchers to explore the therapeutic potential of Sortilin inhibition in relevant biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1531634-31-7 |
| Applications | Sortilin Inhibitor |
| Formula | C15H11F3N2O3 |
| Molecular Weight | 324.25 |
| SMILES | O=C(NC1=CC=CC(C)=N1)C2=CC=C(C(F)(F)F)C=C2C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.