Fig. 1 · Structure
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AF40431
Sortilin Ligand
AF40431 is a small-molecule ligand specifically targeting sortilin, exhibiting an IC50 of 4.4 µM and a Kd of 0.7 µM. It binds within the neurotensin-binding site of sortilin, facilitating its study in various biological contexts. This compound is valuable for investigating sortilin's role in neurobiology and its implications in disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 181125-92-8 |
| Applications | Sortilin Ligand |
| Formula | C17H21NO5 |
| Molecular Weight | 319.35 |
| SMILES | CC(C)C[C@@H](C(O)=O)NCC1=C(O2)C(C(C)=CC2=O)=CC=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.