Fig. 1 · Structure
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AFMK
Antioxidant Metabolite
AFMK (N-acetyl-N'-formyl-5-methoxykynuramine) is an antioxidant metabolite of Melatonin. It has been shown to reduce X-ray-induced oxidative damage to DNA, proteins, and lipids in murine models. Although it is a less effective scavenger compared to its parent compound, AFMK enhances the anti-tumor effects of Gemcitabine in PANC-1 pancreatic cancer cells by modulating apoptotic pathways. This compound is a valuable tool for studies investigating oxidative stress and potential therapeutic strategies for cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 52450-38-1 |
| Applications | Antioxidant Metabolite |
| Formula | C13H16N2O4 |
| Molecular Weight | 264.28 |
| SMILES | CC(NCCC(C1=CC(OC)=CC=C1NC=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.