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Afovirsen

HPV

Afovirsen is a 20-mer phosphorothioate oligonucleotide that specifically targets the mRNA sequence for the translation initiation codon of the E2 protein, essential for the replication of Human Papillomavirus (HPV) types 6 and 11. By disrupting E2 protein synthesis, Afovirsen exhibits potential antiviral activity against HPV, making it a valuable tool for research focused on viral replication mechanisms and therapeutic interventions in HPV-related conditions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	151356-08-0
Applications	HPV
Formula	C₁₉₂H₂₆₉N₅₇O₁₀₇P₁₉S₁₉
Molecular Weight	6285.23
Synonyms	ISIS 2105

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.