AG-120 (Ivosidenib) racemic

Catalog No.: A14386
IDH1 inhibitor
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
AG-120 5mg
$120.00
In stock
AG-120 10mg
$220.00
In stock
AG-120 25mg
$450.00
In stock
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Biological Activity
Discription AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.
Product Information
Catalog Num A14386
Formula C28H22ClF3N6O3
Molecular Weight 582.97
CAS Number 1448346-63-1
SMILES C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
Synonyms AG120, AG 120, Ivosidenib
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 95 mg/mL (162.95 mM)
Water Insoluble
Ethanol 95 mg/mL (162.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.15 mL 85.77 mL 171.54 mL
0.5 mM 3.43 mL 17.15 mL 34.31 mL
1 mM 1.72 mL 8.58 mL 17.15 mL
5 mM 0.34 mL 1.72 mL 3.43 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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