AG-494

Catalog No.: A17142

EGFR inhibitor

AG-494

AG-494 Chemical Structure

CAS NO. 133550-35-3

AG-494 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 μM in HT-22 cells.

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$80.00
50 mg
$140.00
100 mg
$240.00
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Biological Activity

AG-494 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 μM in HT-22 cells.
In vitro DMSO 50 mg/mL (178.39 mM)
Water Insoluble
Ethanol 4 mg/mL (14.27 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.68 mL 178.39 mL 356.79 mL
0.5 mM 7.14 mL 35.68 mL 71.36 mL
1 mM 3.57 mL 17.84 mL 35.68 mL
5 mM 0.71 mL 3.57 mL 7.14 mL

*The above data is based on the productmolecular weight 280.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17142
Actions Inhibitor
CAS No. 133550-35-3
Formula C16H12N2O3
M. Wt 280.28
Solubility DMSO
Purity >98%
Synonyms Tyrphostin AG-494, AG494, AG 494
SMILES O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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