AG-494 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 μM in HT-22 cells.
Targets
Target
Value
Product Information
Catalog Num
A17142
Formula
C16H12N2O3
Molecular Weight
280.28
CAS Number
133550-35-3
SMILES
O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Synonyms
Tyrphostin AG-494, AG494, AG 494
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
50 mg/mL (178.39 mM)
Water
Insoluble
Ethanol
4 mg/mL (14.27 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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