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AGH-107

5-HT7 Receptor Agonist

AGH-107 is a highly selective agonist of the 5-HT7 receptor, demonstrating a Ki of 6 nM and an EC50 of 19 nM. It exhibits considerable brain penetration, along with high selectivity for the 5-HT7 receptor over related CNS targets. AGH-107 has also been shown to possess high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures, making it a valuable tool for studying serotonergic signaling and its implications in neuropsychiatric disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	2172907-10-5
Applications	5-HT7 Receptor Agonist
Formula	C₁₃H₁₂IN₃
Molecular Weight	337.16
SMILES	IC1=CC=C2NC=C(C3=CN=CN3CC)C2=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.