AGI-12026

Name: AGI-12026
Brand: Adooq Bioscience
SKU: A75815
Rating: 5 (288 reviews)

Catalog No.: A75815

IDH1/2 Modulator

AGI-12026 is a brain-penetrant dual inhibitor targeting mutant isocitrate dehydrogenase 1 and 2 (IDH1/2). It acts as an allosteric modulator, demonstrating partial inhibition of the IDH1-R132H homodimer. This compound is suitable for research applications related to glioma and provides a valuable tool for studying the role of mutant IDH enzymes in cancer biology.

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Grouped product items
Size	Price	Stock
1mg	$235.00	In stock
5mg	$590.00	In stock
10mg	$830.00	In stock
25mg	$1,275.00	In stock
50mg	$1,625.00	In stock
100mg	$2,000.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	AGI-12026 is a brain-penetrant dual inhibitor targeting mutant isocitrate dehydrogenase 1 and 2 (IDH1/2). It acts as an allosteric modulator, demonstrating partial inhibition of the IDH1-R132H homodimer. This compound is suitable for research applications related to glioma and provides a valuable tool for studying the role of mutant IDH enzymes in cancer biology.

Product Information

Catalog Num	A75815
Formula	C18H15F6N7
Molecular Weight	443.35
CAS Number	1446501-77-4
SMILES	FC(F)(F)C1=CC=CC(C2=NC(NC(C)C)=NC(NC3=CC(C(F)(F)F)=NC=C3)=N2)=N1
Synonyms	AGI-026

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