Aha1/Hsp90-IN-1

Catalog No.: A54938
Aha1/Hsp90 Complex Inhibitor
Aha1/Hsp90-IN-1 is a potent inhibitor of the Aha1/Hsp90 complex, demonstrating an IC50 value of 3.32 μM. By disrupting the interactions between Aha1 and Hsp90, this compound effectively inhibits tau aggregation. Research applications include studies of protein folding and aggregation diseases, making it a valuable tool in the exploration of neurodegenerative disorders.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAha1/Hsp90-IN-1 is a potent inhibitor of the Aha1/Hsp90 complex, demonstrating an IC50 value of 3.32 μM. By disrupting the interactions between Aha1 and Hsp90, this compound effectively inhibits tau aggregation. Research applications include studies of protein folding and aggregation diseases, making it a valuable tool in the exploration of neurodegenerative disorders.
Product Information
Catalog NumA54938
FormulaC22H17F3N4O2
Molecular Weight426.39
CAS Number2768265-58-1
SMILESCOC1=CC(C2=C(C=CC(C3=NN=NN3C4=CC=C(C=C4)C(F)(F)F)=C2)OC)=CC=C1
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