Fig. 1 · Structure
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AHR-13268D
Antiallergic/Antihistaminic Agent
AHR-13268D is a potent antiallergic and antihistaminic agent, primarily acting as an inhibitor of histamine release from mast cells. With an oral bioavailability of approximately 88%, it demonstrates significant efficacy in reducing allergenic responses, as evidenced by its IC50 value of 0.51 nM in rat peritoneal mast cells. This compound is valuable for research applications focused on allergy-related studies and mast cell biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 130838-11-8 |
| Applications | Antiallergic/Antihistaminic Agent |
| Formula | C28H28F2NNaO4 |
| Molecular Weight | 503.51 |
| SMILES | O=C(C1=CC=C(C=C1)OCCCN2CCC(CC2)C(C3=CC=C(C=C3)F)(O)C4=CC=C(C=C4)F)O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.