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AHR-2244 hydrochloride

Anxiolytics

AHR-2244 hydrochloride is a selective antagonist of the constitutive androstane receptor (CAR), primarily utilized in research related to anxiety and psychosis. This compound demonstrates significant anxiolytic activity, effectively mitigating anxiety symptoms in preclinical models such as mice and rats. Additionally, AHR-2244 hydrochloride has been shown to reduce amphetamine-related lethality, making it a valuable tool for investigating the mechanisms underlying anxiety and related disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	24677-84-7
Applications	Anxiolytics
Formula	C₂₄H₂₉ClFNO₄
Molecular Weight	449.94
SMILES	CC(C1=CC=C(C(OC)=C1)OCCCN2CCC(CC2)C(C3=CC=C(C=C3)F)=O)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.