AHR Agonist 3 is a potent agonist of the aryl hydrocarbon receptor (AhR) that induces cell cycle arrest and apoptosis by activating tumor-suppressive transcriptional programs. It effectively inhibits the growth of stem cells in triple-negative breast cancer (TNBC) while demonstrating low cytotoxicity towards normal human primary cells. This compound is a valuable tool for cancer research, particularly in studies focused on TNBC and the mechanisms underlying AhR-mediated signaling pathways.
AHR Agonist 3 is a potent agonist of the aryl hydrocarbon receptor (AhR) that induces cell cycle arrest and apoptosis by activating tumor-suppressive transcriptional programs. It effectively inhibits the growth of stem cells in triple-negative breast cancer (TNBC) while demonstrating low cytotoxicity towards normal human primary cells. This compound is a valuable tool for cancer research, particularly in studies focused on TNBC and the mechanisms underlying AhR-mediated signaling pathways.
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