Fig. 1 · Structure
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AIP-II
QS Signaling Molecule
AIP-II is a macrocyclic peptide that functions as a signaling molecule in quorum sensing, primarily produced by Staphylococcus aureus. It specifically binds to the AgrC-II receptor, modulating the expression of virulence genes in this bacterial pathogen. Additionally, AIP-II serves as an antagonist of the AgrC-I receptor, making it a valuable tool for research on bacterial communication and virulence regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 200010-31-7 |
| Applications | QS Signaling Molecule |
| Formula | C38H58N10O12S |
| Molecular Weight | 878.99 |
| SMILES | C([C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)[C@H](C)C)=O)CC(N)=O)=O)C)=O)CSC1=O)C2=CC=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.