Fig. 1 · Structure

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AJ-76 hydrochloride

Dopamine

AJ-76 hydrochloride is a potent antagonist of dopamine autoreceptors, exhibiting pKi values of 6.95, 6.67, 6.37, 6.21, and 6.07 for human D3, D4, D2 short, D2 long, and rat D2 receptors, respectively. This compound is valuable for research focused on dopamine receptor modulation and its implications in neurological disorders. Its specific receptor affinity allows for investigations into the roles of dopamine signaling in various physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 85378-82-1
Applications Dopamine
Formula C15H24ClNO
Molecular Weight 269.81
Synonyms (+)-AJ 76 hydrochloride; (1S,2R)-AJ 76 hydrochloride
SMILES
CCCN[C@H]1[C@@H](C)C2=C(C(OC)=CC=C2)CC1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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