Fig. 1 · Structure
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AK-IN-1
AK Inhibitor
AK-IN-1 is a competitive inhibitor of adenosine kinase (AK), specifically targeting adenosine without competing with ATP. It effectively reduces AK activity by 86%, 87%, and 89% at concentrations of 2, 4, and 10 µM, respectively. This compound has significant potential for research in various disease contexts, including ischaemia, inflammation, and seizure disorders, making it a valuable tool for elucidating the role of adenosine signaling in these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 378775-98-5 |
| Applications | AK Inhibitor |
| Formula | C22H21N3O4 |
| Molecular Weight | 391.42 |
| SMILES | OCCNC1=NC=NC2=C1C(C3=CC=C(OC)C=C3)=C(C4=CC=C(C=C4)OC)O2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.