Fig. 1 · Structure
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AKR1C1-IN-1
AKR1C1 Inhibitor
AKR1C1-IN-1 is a selective inhibitor of human 20α-hydroxysteroid dehydrogenase (AKR1C1), exhibiting a Ki value of 4 nM. This compound demonstrates significant inhibitory activity, making it a valuable tool for studying AKR1C1-related biological processes. Its applications include investigating steroid metabolism and exploring potential therapeutic targets in hormone-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4906-68-7 |
| Applications | AKR1C1 Inhibitor |
| Formula | C13H9BrO3 |
| Molecular Weight | 293.11 |
| SMILES | O=C(C1=CC(C2=CC=CC=C2)=CC(Br)=C1O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.