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AKR1C3-IN-10

AKR1C3 Inhibitor

AKR1C3-IN-10 is a selective inhibitor of aldo-keto reductase 1C3 (AKR1C3), with an IC50 value of 51 nM. This compound exhibits significant antitumor activity in prostate cancer xenograft models, making it a valuable tool for cancer research. It is particularly relevant for studies focused on the modulation of steroid metabolism and the development of therapeutic strategies targeting AKR1C3 in cancer.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3028287-43-3
Applications	AKR1C3 Inhibitor
Formula	C₂₄H₂₀N₄O₃
Molecular Weight	412.44
SMILES	O=C(C1=CC(C(C=C2)=CN3C2=NC=N3)=CC(/C=C/C(O)=O)=C1)NCC4=CC=C(C=C4)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.