AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibiting an IC50 value of 0.56 μM. This compound is particularly relevant for investigations into castrate-resistant prostate cancer (CRPC), where AKR1C3 plays a crucial role in tumor progression and hormone regulation. Its mechanism facilitates the exploration of therapeutic strategies targeting metabolic pathways in cancer research.
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibiting an IC50 value of 0.56 μM. This compound is particularly relevant for investigations into castrate-resistant prostate cancer (CRPC), where AKR1C3 plays a crucial role in tumor progression and hormone regulation. Its mechanism facilitates the exploration of therapeutic strategies targeting metabolic pathways in cancer research.
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