Akt1-IN-3

Catalog No.: A25810
AKT1 Inhibitor
Akt1-IN-3 is a selective inhibitor of AKT1, demonstrating potent inhibition with an IC50 value of less than 15 nM against the AKT1-E17K mutant. This compound is valuable for research applications exploring the role of AKT signaling in various cancers and other diseases. Its potency and specificity make it an essential tool for studies aimed at understanding AKT1-related pathways and developing targeted therapies.
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAkt1-IN-3 is a selective inhibitor of AKT1, demonstrating potent inhibition with an IC50 value of less than 15 nM against the AKT1-E17K mutant. This compound is valuable for research applications exploring the role of AKT signaling in various cancers and other diseases. Its potency and specificity make it an essential tool for studies aimed at understanding AKT1-related pathways and developing targeted therapies.
Product Information
Catalog NumA25810
FormulaC37H33N7O3
Molecular Weight623.70
CAS Number3033576-50-7
SMILESNC1=C(C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(CN6CCC(NC(C7=CC(C=O)=C(O)C=C7)=O)CC6)C=C5)C=CC=N1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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