AL-34662 is a selective agonist of the 5-HT2A receptor, exhibiting an IC50 of 0.77 nM for the rat receptor and 1.5 nM for the human receptor. In addition to its primary activity, AL-34662 demonstrates weak α-1D adrenergic agonist properties with an EC50 of 0.4 μM. This compound is primarily studied for its ocular hypotensive effects and has potential applications in the treatment of glaucoma and other ocular conditions.
AL-34662 is a selective agonist of the 5-HT2A receptor, exhibiting an IC50 of 0.77 nM for the rat receptor and 1.5 nM for the human receptor. In addition to its primary activity, AL-34662 demonstrates weak α-1D adrenergic agonist properties with an EC50 of 0.4 μM. This compound is primarily studied for its ocular hypotensive effects and has potential applications in the treatment of glaucoma and other ocular conditions.
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