Fig. 1 · Structure
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AL-34662
5-HT2A Receptor Agonist
AL-34662 is a selective agonist of the 5-HT2A receptor, exhibiting an IC50 of 0.77 nM for the rat receptor and 1.5 nM for the human receptor. In addition to its primary activity, AL-34662 demonstrates weak α-1D adrenergic agonist properties with an EC50 of 0.4 μM. This compound is primarily studied for its ocular hypotensive effects and has potential applications in the treatment of glaucoma and other ocular conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 210580-75-9 |
| Applications | 5-HT2A Receptor Agonist |
| Formula | C10H13N3O |
| Molecular Weight | 191.23 |
| SMILES | OC1=CC2=C(C=C1)C=NN2C[C@@H](N)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.