AL-438 is a selective glucocorticoid receptor modulator that exhibits potent activity with a Ki of 2.5 nM for the glucocorticoid receptor, along with lower affinities for other steroid receptors. This compound demonstrates significant anti-inflammatory properties, making it a valuable tool for research focused on inflammation and endocrine signaling pathways. Its oral bioavailability enhances its utility for in vivo studies in various therapeutic contexts.
AL-438 is a selective glucocorticoid receptor modulator that exhibits potent activity with a Ki of 2.5 nM for the glucocorticoid receptor, along with lower affinities for other steroid receptors. This compound demonstrates significant anti-inflammatory properties, making it a valuable tool for research focused on inflammation and endocrine signaling pathways. Its oral bioavailability enhances its utility for in vivo studies in various therapeutic contexts.
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