Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a selective agonist for Protease-Activated Receptor 1 (PAR-1), distinguishing it from PAR-2. This bioactive peptide mediates the cellular effects associated with thrombin and plays a significant role in various thrombin-related cellular activities. Furthermore, PAR-1 is implicated in the regulation of thrombin-induced hepatocellular carcinoma, highlighting its relevance in tumor microenvironments characterized by coagulation factors. This compound is essential for studies focusing on PAR-1 signaling pathways and thrombin-related pathophysiology.
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a selective agonist for Protease-Activated Receptor 1 (PAR-1), distinguishing it from PAR-2. This bioactive peptide mediates the cellular effects associated with thrombin and plays a significant role in various thrombin-related cellular activities. Furthermore, PAR-1 is implicated in the regulation of thrombin-induced hepatocellular carcinoma, highlighting its relevance in tumor microenvironments characterized by coagulation factors. This compound is essential for studies focusing on PAR-1 signaling pathways and thrombin-related pathophysiology.
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