ALAPYIP

Catalog No.: A80655
Ligand for E3 Ligase
ALAPYIP is a specific ligand for E3 ubiquitin ligase, effectively recruiting the VHL-E3 ligase. This compound plays a critical role in ubiquitination processes and can be utilized in the synthesis of FPP29. ALAPYIP is valuable for research aimed at understanding protein degradation pathways and the regulation of cellular processes through controlled ubiquitin signaling.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionALAPYIP is a specific ligand for E3 ubiquitin ligase, effectively recruiting the VHL-E3 ligase. This compound plays a critical role in ubiquitination processes and can be utilized in the synthesis of FPP29. ALAPYIP is valuable for research aimed at understanding protein degradation pathways and the regulation of cellular processes through controlled ubiquitin signaling.
Product Information
Catalog NumA80655
FormulaC37H57N7O9
Molecular Weight743.89
CAS Number1260529-82-5
SequenceAla-Leu-Ala-Pro-Tyr-Ile-Pro
Sequence shorteningALAPYIP
SMILESO=C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2