Fig. 1 · Structure
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ALC-0315
Lipid Nanoparticle Component
ALC-0315 is an ionizable aminolipid that facilitates the compaction of mRNA and enhances its delivery into cells, promoting cytoplasmic release via endosomal destabilization. This compound plays a crucial role in the formation of lipid nanoparticle (LNP) delivery vehicles, making it an important reagent in mRNA vaccine research, particularly for applications related to COVID-19 vaccine development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2036272-55-4 |
| Applications | Lipid Nanoparticle Component |
| Formula | C48H95NO5 |
| Molecular Weight | 766.27 |
| SMILES | OCCCCN(CCCCCCOC(C(CCCCCC)CCCCCCCC)=O)CCCCCCOC(C(CCCCCC)CCCCCCCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.