Fig. 1 · Structure
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ALC67
Thiazolidine
ALC67 is a cytotoxic thiazolidine compound that exhibits an IC50 of approximately 5 μM against various cancer cell lines, including liver, breast, colon, and endometrial cancers. The compound induces apoptosis by activating caspase-9 and causing cell cycle arrest at the SubG1/G1 phase, operating through a pathway that does not involve death receptors. ALC67 is suitable for use in cancer research to investigate its mechanisms of action and therapeutic potential.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1044255-57-3 |
| Applications | Thiazolidine |
| Formula | C15H15NO3S |
| Molecular Weight | 289.35 |
| SMILES | O=C([C@H]1N(C(C#C)=O)C(C2=CC=CC=C2)SC1)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.