Fig. 1 · Structure
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ALDH2 modulator 1
ALDH2 modulator
ALDH2 Modulator 1 is a potent modulator of aldehyde dehydrogenase-2 (ALDH2), showcasing effective oral bioavailability. This compound has been demonstrated to significantly reduce blood alcohol levels in murine models, highlighting its potential applications in alcohol metabolism research and related metabolic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1629615-99-1 |
| Applications | ALDH2 modulator |
| Formula | C18H18ClFN2O3 |
| Molecular Weight | 364.80 |
| SMILES | O=C(C1=C(C=CN=C1OCC2CC2)Cl)NCC3=CC=C(C(F)=C3)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.