Aldi-2 is a selective covalent inhibitor of aldehyde dehydrogenases (ALDHs), exhibiting IC50 values of 2.5, 6.4, and 1.9 μM for ALDH1A1, ALDH2, and ALDH3A1, respectively. This compound is particularly valuable in cancer research, providing insight into the role of ALDHs in tumor metabolism and progression. Its specificity allows for targeted studies on the modulation of ALDH activity within various biological contexts.
Aldi-2 is a selective covalent inhibitor of aldehyde dehydrogenases (ALDHs), exhibiting IC50 values of 2.5, 6.4, and 1.9 μM for ALDH1A1, ALDH2, and ALDH3A1, respectively. This compound is particularly valuable in cancer research, providing insight into the role of ALDHs in tumor metabolism and progression. Its specificity allows for targeted studies on the modulation of ALDH activity within various biological contexts.
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