Fig. 1 · Structure
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Alfuzosin
α1-Adrenoceptor Antagonist
Alfuzosin is a selective, competitive antagonist of the α1-adrenoceptor, primarily functioning to inhibit the activity of this receptor subtype. Its biological activity leads to the relaxation of smooth muscles in the prostate and bladder neck, thereby facilitating urination. This compound is valuable for research applications focused on benign prostatic hyperplasia (BPH) and related urological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 81403-80-7 |
| Applications | α1-Adrenoceptor Antagonist |
| Formula | C19H27N5O4 |
| Molecular Weight | 389.45 |
| Synonyms | SL 77499 |
| SMILES | O=C(C1OCCC1)NCCCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.