Fig. 1 · Structure
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Alimemazine
HA Receptor Antagonist
Alimemazine is a phenothiazine derivative that acts as an antagonist of the hemagglutinin (HA) receptor. This compound exhibits key biological activities, including antipruritic, antiserotonin, antispasmodic, and antiemetic effects. Alimemazine also functions as a partial agonist at the histamine H1 receptor and various G protein-coupled receptors (GPCRs), making it useful for research in pharmacology and neurobiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 84-96-8 |
| Applications | HA Receptor Antagonist |
| Formula | C18H22N2S |
| Molecular Weight | 298.45 |
| Synonyms | Trimeprazine |
| SMILES | CC(CN(C)C)CN1C2=CC=CC=C2SC3=CC=CC=C31 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.