Fig. 1 · Structure
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ALKBH5-IN-4
ALKBH5 Inhibitor
ALKBH5-IN-4 is an inhibitor of the RNA m6A demethylase ALKBH5, exhibiting an IC50 value of 0.84 μM. This compound has demonstrated inhibitory effects on leukemia cells, highlighting its potential role in cancer research. ALKBH5-IN-4 can be utilized to study the biological implications of m6A methylation in various cellular contexts and may serve as a valuable tool in the development of novel therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 37510-29-5 |
| Applications | ALKBH5 Inhibitor |
| Formula | C10H10O4S |
| Molecular Weight | 226.25 |
| SMILES | O=C(O)CSC(O)C(C1=CC=CC=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.