Fig. 1 · Structure
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Almotriptan hydrochloride
5-HT Receptor Agonist
Almotriptan hydrochloride is a selective agonist of the 5-HT 1B and 1D receptors, primarily targeting serotonin receptors involved in vascular regulation. This compound demonstrates significant efficacy in the treatment of migraine attacks by promoting vasoconstriction and inhibiting pro-inflammatory neuropeptide release. Almotriptan hydrochloride is utilized in various research applications focused on migraine mechanisms and the physiological role of serotonin in headache disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 154323-46-3 |
| Applications | 5-HT Receptor Agonist |
| Formula | C17H26ClN3O2S |
| Molecular Weight | 371.93 |
| SMILES | CN(CCC1=CNC2=C1C=C(CS(=O)(N3CCCC3)=O)C=C2)C.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.