Fig. 1 · Structure
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Alniditan dihydrochloride
5-HT1B/1D Receptors Agonist
Alniditan dihydrochloride is a selective agonist of the 5-HT1B and 5-HT1D receptors, exhibiting IC50 values of 1.7 nM and 1.3 nM, respectively, in HEK293 cells. This compound demonstrates significant efficacy in preventing migraines, making it a valuable tool in migraine research. Its potent action on serotonin receptors highlights its potential applications in the study of headache disorders and related therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 155428-00-5 |
| Applications | 5-HT1B/1D Receptors Agonist |
| Formula | C17H28Cl2N4O |
| Molecular Weight | 375.34 |
| Synonyms | Alnitidan dihydrochloride |
| SMILES | [H]Cl.[H]Cl.C1(NCCCNC[C@H]2CCC3=CC=CC=C3O2)=NCCCN1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.