Fig. 1 · Structure
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alpha-1,3-Galactosyltransferase (GTB)
α-Gal Epitope Synthesis
Alpha-1,3-Galactosyltransferase (GTB) primarily facilitates the synthesis of the α-galactose (α-Gal) epitope, a significant xenoantigen. GTB catalyzes the transfer of galactose from UDP-Gal to type 1 or type 2 acceptors, specifically αFuc1→2βGal-R (H)-terminating structures. This enzyme is crucial for research applications involving xenotransplantation and immunology, particularly in the study of host immune responses to genetically modified tissues expressing the α-Gal epitope.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 37257-33-3 |
| Applications | α-Gal Epitope Synthesis |
| Synonyms | alpha 1,3GT |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.