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alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 44.97 mL | 224.85 mL | 449.7 mL |
| 0.5 mM | 8.99 mL | 44.97 mL | 89.94 mL |
| 1 mM | 4.5 mL | 22.49 mL | 44.97 mL |
| 5 mM | 0.9 mL | 4.5 mL | 8.99 mL |
*The above data is based on the productmolecular weight 222.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18691 |
|---|---|
| CAS No. | 515-69-5 |
| Formula | C15H26O |
| M. Wt | 222.37 |
| Purity | >98% |
| SMILES | C/C(C)=C\CC[[email protected]@](O)([[email protected]@H]1CCC(C)=CC1)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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