Alpha-Mangostin is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1-R132H), demonstrating a Ki of 2.85 μM. This dietary xanthone exhibits a diverse range of biological activities, including antioxidant, anti-inflammatory, antibacterial, and anticancer properties. It is valuable for research applications exploring metabolic pathways in cancer and the development of targeted therapies against IDH1-mutant tumors.
Alpha-Mangostin is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1-R132H), demonstrating a Ki of 2.85 μM. This dietary xanthone exhibits a diverse range of biological activities, including antioxidant, anti-inflammatory, antibacterial, and anticancer properties. It is valuable for research applications exploring metabolic pathways in cancer and the development of targeted therapies against IDH1-mutant tumors.
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