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Biological Activity
Alvespimycin is a selective Hsp90 inhibitor with a GI50 of 53 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.21 mL | 81.07 mL | 162.14 mL |
| 0.5 mM | 3.24 mL | 16.21 mL | 32.43 mL |
| 1 mM | 1.62 mL | 8.11 mL | 16.21 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
*The above data is based on the productmolecular weight 616.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14990 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 467214-20-6 |
| Formula | C32H48N4O8 |
| M. Wt | 616.75 |
| Purity | >98% |
| Synonyms | 17-DMAG, KOS-1022, NSC707545 |
| SMILES | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)C)OC)OC(=O)N)C)C)O)OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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