Fig. 1 · Structure
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ALW-II-38-3
EphA3 Inhibitor
AWL-II-38.3 is a selective inhibitor of the ephrin-A receptor (EphA3) kinase. This compound demonstrates potent inhibitory activity specifically targeting EphA3 while displaying minimal effects on Src-family kinases and b-raf. Its specificity makes AWL-II-38.3 valuable for research applications involving EphA3-mediated signaling pathways and related cellular processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1135205-94-5 |
| Applications | EphA3 Inhibitor |
| Formula | C23H18F3N5O3 |
| Molecular Weight | 469.42 |
| SMILES | O=C(C1=CC=NO1)NC2=CC(NC(C3=CC(C(F)(F)F)=CC(N4C=NC(C)=C4)=C3)=O)=CC=C2C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.