AM-2099

Catalog No.: A12463

Nav1.7 inhibitor

AM-2099

AM-2099 Chemical Structure

CAS NO. 1443373-17-8

AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 with an IC50 of 0.16 μM for human Nav1.7.

Availability: In stock

Package Price Qty
5 mg
$81.00
10 mg
$140.00
50 mg
$414.00
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Biological Activity

AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 with an IC50 of 0.16 μM for human Nav1.7.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.44 mL 107.19 mL 214.38 mL
0.5 mM 4.29 mL 21.44 mL 42.88 mL
1 mM 2.14 mL 10.72 mL 21.44 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12463
Actions Inhibitor
CAS No. 1443373-17-8
Formula C19H13F3N4O3S2
M. Wt 466.46
Solubility DMSO
Purity >98%
Synonyms AM-2099, AM2099
SMILES COC1=CC(C(F)(F)F)=CC=C1C2=NC=NC3=CC(S(=O)(NC4=NC=CS4)=O)=CC=C32
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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