Fig. 1 · Structure
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AM-36
Neuroprotective Agent
AM-36 is a neuroprotective agent that exhibits both antioxidant properties and sodium channel blocking activity. This compound has demonstrated the ability to inhibit cell apoptosis and reduce reactive oxygen species (ROS) production. In preclinical studies, AM-36 has been shown to mitigate neuronal damage and dopamine (DA) release following middle cerebral artery occlusion in rat models. It is a valuable reagent for research into inflammation and various neurological disorders, including stroke.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 199467-52-2 |
| Applications | Neuroprotective Agent |
| Formula | C27H39ClN2O2 |
| Molecular Weight | 459.06 |
| SMILES | ClC1=CC=C(C(CN2CCN(CC2)CC3=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C3)O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.